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Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6∊-FCR3 of the Plasmodium falciparum VAR2CSA protein
The VAR2CSA protein has been closely associated with pregnancy-associated malaria and is recognized as the main adhesin exposed on the surface of Plasmodium falciparum-infected erythrocytes. Chondroitin sulfate A was identified as the main host receptor in the placenta. Single-domain heavy-chain cam...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
International Union of Crystallography
2013
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606572/ https://ncbi.nlm.nih.gov/pubmed/23519802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113001917 |
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