MECHANISMS OF EMPHYSEMA IN AUTOSOMAL DOMINANT CUTIS LAXA

Heterozygous elastin gene mutations cause autosomal dominant cutis laxa associated with emphysema and aortic aneurysms. To investigate the molecular mechanisms leading to cutis laxa in vivo, we generated transgenic mice by pronuclear injection of minigenes encoding normal human tropoelastin (WT) or...

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Qirui, Shifren, Adrian, Sens, Carla, Choi, Jiwon, Szabo, Zoltan, Starcher, Barry C., Knutsen, Russell H., Shipley, J. Michael, Davis, Elaine C., Mecham, Robert P., Urban, Zsolt
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606561/
https://ncbi.nlm.nih.gov/pubmed/20600892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2010.06.005
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