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FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2

The Rho-associated coiled-coil containing kinases, ROCK1 and ROCK2, are important regulators of cell shape, migration, and proliferation through effects on the actin cytoskeleton. However, it is not known whether ROCK2 plays an important role in the development of cardiac hypertrophy. To determine w...

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Hlavní autoři: Okamoto, Ryuji, Li, Yuxin, Noma, Kensuke, Hiroi, Yukio, Liu, Ping-Yen, Taniguchi, Masaya, Ito, Masaaki, Liao, James K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606529/
https://ncbi.nlm.nih.gov/pubmed/23271052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217018
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