The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

Muramyl dipeptide (MDP), a product of bacterial cell-wall peptidoglycan, activatesinnate immune cells by stimulating nucleotide-binding oligomerization domain containing 2 (NOD2) -dependent activation of the transcription factor NFκB and transcription of proinflammatory genes. A20 is a ubiquitin-mod...

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Bibliografiske detaljer
Main Authors: Hitotsumatsu, Osamu, Ahmad, Regina-Celeste, Tavares, Rita, Wang, Min, Philpott, Dana, Turer, Emre E., Lee, Bettina L., Shiffin, Nataliya, Advincula, Rommel, Malynn, Barbara A., Werts, Catherine, Ma, Averil
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606373/
https://ncbi.nlm.nih.gov/pubmed/18342009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.02.002
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