Transcriptional Suppression, DNA Methylation, and Histone Deacetylation of the Regulator of G-Protein Signaling 10 (RGS10) Gene in Ovarian Cancer Cells

RGS10 regulates ovarian cancer cell growth and survival, and RGS10 expression is suppressed in cell models of ovarian cancer chemoresistance. However, the mechanisms governing RGS10 expression in ovarian cancer are poorly understood. Here we report RGS10 suppression in primary ovarian cancer and CAO...

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Hauptverfasser: Ali, Mourad W., Cacan, Ercan, Liu, Yuying, Pierce, Jennifer Young, Creasman, William T., Murph, Mandi M., Govindarajan, Rajgopal, Eblen, Scott T., Greer, Susanna F., Hooks, Shelley B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606337/
https://ncbi.nlm.nih.gov/pubmed/23533674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060185
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