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Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells

BACKGROUND: A critical therapeutic challenge in epithelial ovarian carcinoma is the development of chemoresistance among tumor cells following exposure to first line chemotherapeutics. The molecular and genetic changes that drive the development of chemoresistance are unknown, and this lack of mecha...

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Detalhes bibliográficos
Main Authors: Hooks, Shelley B, Callihan, Phillip, Altman, Molly K, Hurst, Jillian H, Ali, Mourad W, Murph, Mandi M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988731/
https://ncbi.nlm.nih.gov/pubmed/21044322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-289
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