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Regulators of G-Protein signaling RGS10 and RGS17 regulate chemoresistance in ovarian cancer cells

BACKGROUND: A critical therapeutic challenge in epithelial ovarian carcinoma is the development of chemoresistance among tumor cells following exposure to first line chemotherapeutics. The molecular and genetic changes that drive the development of chemoresistance are unknown, and this lack of mecha...

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Autores principales: Hooks, Shelley B, Callihan, Phillip, Altman, Molly K, Hurst, Jillian H, Ali, Mourad W, Murph, Mandi M
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988731/
https://ncbi.nlm.nih.gov/pubmed/21044322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-289
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