Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells

The regulator of G protein signaling 10 (RGS10) protein is a GTPase activating protein that accelerates the hydrolysis of GTP and therefore canonically inactivates G proteins, ultimately terminating signaling. Rheb is a small GTPase protein that shuttles between its GDP- and GTP-bound forms to activ...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cancer Lett
Main Authors: Altman, Molly K., Alshamrani, Ali A., Jia, Wei, Nguyen, Ha, Fambrough, Jada M., Tran, Sterling K., Patel, Mihir, Hoseinzadeh, Pooya, Beedle, Aaron M., Murph, Mandi M.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654121/
https://ncbi.nlm.nih.gov/pubmed/26319900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.08.012
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares