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Biochemical Identification of a Linear Cholesterol-Binding Domain within Alzheimer’s β Amyloid Peptide
[Image: see text] Alzheimer’s β-amyloid (Aβ) peptides can self-organize into amyloid pores that may induce acute neurotoxic effects in brain cells. Membrane cholesterol, which regulates Aβ production and oligomerization, plays a key role in this process. Although several data suggested that choleste...
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| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2012
|
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605813/ https://ncbi.nlm.nih.gov/pubmed/23509984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300203a |
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