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Biochemical Identification of a Linear Cholesterol-Binding Domain within Alzheimer’s β Amyloid Peptide

[Image: see text] Alzheimer’s β-amyloid (Aβ) peptides can self-organize into amyloid pores that may induce acute neurotoxic effects in brain cells. Membrane cholesterol, which regulates Aβ production and oligomerization, plays a key role in this process. Although several data suggested that choleste...

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Detalhes bibliográficos
Main Authors: Di Scala, Coralie, Yahi, Nouara, Lelièvre, Clément, Garmy, Nicolas, Chahinian, Henri, Fantini, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605813/
https://ncbi.nlm.nih.gov/pubmed/23509984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300203a
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