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How Cholesterol Constrains Glycolipid Conformation for Optimal Recognition of Alzheimer's β Amyloid Peptide (Aβ(1-40))

Membrane lipids play a pivotal role in the pathogenesis of Alzheimer's disease, which is associated with conformational changes, oligomerization and/or aggregation of Alzheimer's β-amyloid (Aβ) peptides. Yet conflicting data have been reported on the respective effect of cholesterol and gl...

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Bibliografiske detaljer
Main Authors: Yahi, Nouara, Aulas, Anaïs, Fantini, Jacques
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816720/
https://ncbi.nlm.nih.gov/pubmed/20140095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009079
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