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PD-L1/PD-1 Co-Stimulation, a Brake for T cell Activation and a T cell Differentiation Signal

For T cell activation, three signals have to be provided from the antigen presenting cell; Signal 1 (antigen recognition), signal 2 (co-stimulation) and signal 3 (cytokine priming). Blocking negative co-stimulation during antigen presentation to T cells is becoming a promising therapeutic strategy t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liechtenstein, Therese, Dufait, Ines, Bricogne, Christopher, Lanna, Alessio, Pen, Joeri, Breckpot, Karine, Escors, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605779/
https://ncbi.nlm.nih.gov/pubmed/23525238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.S12-006
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