Polymorphism in Human Cytomegalovirus UL40 Impacts on Recognition of Human Leukocyte Antigen-E (HLA-E) by Natural Killer Cells

Natural killer (NK) cell recognition of the nonclassical human leukocyte antigen (HLA) molecule HLA-E is dependent on the presentation of a nonamer peptide derived from the leader sequence of other HLA molecules to CD94-NKG2 receptors. However, human cytomegalovirus can manipulate this central innat...

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Bibliographische Detailangaben
Hauptverfasser: Heatley, Susan L., Pietra, Gabriella, Lin, Jie, Widjaja, Jacqueline M. L., Harpur, Christopher M., Lester, Sue, Rossjohn, Jamie, Szer, Jeff, Schwarer, Anthony, Bradstock, Kenneth, Bardy, Peter G., Mingari, Maria Cristina, Moretta, Lorenzo, Sullivan, Lucy C., Brooks, Andrew G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605686/
https://ncbi.nlm.nih.gov/pubmed/23335510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409672
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