HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8(+) cytolytic T lymphocytes

HLA-E-restricted T cell receptor αβ(+) CD8(+) cytolytic T lymphocytes (CTLs) exist as monoclonal expansions in the peripheral blood of some individuals. Here, we show that they recognize, with high avidity, peptides derived from the UL40 protein of different human cytomegalovirus (CMV) strains. Reco...

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Detalhes bibliográficos
Main Authors: Pietra, Gabriella, Romagnani, Chiara, Mazzarino, Paola, Falco, Michela, Millo, Enrico, Moretta, Alessandro, Moretta, Lorenzo, Mingari, Maria Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196899/
https://ncbi.nlm.nih.gov/pubmed/12960383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834449100
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