HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8(+) cytolytic T lymphocytes

HLA-E-restricted T cell receptor αβ(+) CD8(+) cytolytic T lymphocytes (CTLs) exist as monoclonal expansions in the peripheral blood of some individuals. Here, we show that they recognize, with high avidity, peptides derived from the UL40 protein of different human cytomegalovirus (CMV) strains. Reco...

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Bibliographische Detailangaben
Hauptverfasser: Pietra, Gabriella, Romagnani, Chiara, Mazzarino, Paola, Falco, Michela, Millo, Enrico, Moretta, Alessandro, Moretta, Lorenzo, Mingari, Maria Cristina
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2003
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196899/
https://ncbi.nlm.nih.gov/pubmed/12960383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834449100
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