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Nuclease activity associated with mammalian mRNA in its native state: possible basis for selectivity in mRNA decay.

Polysome and messenger ribonucleoprotein (mRNP) preparations from various mammalian cells contain tightly bound nuclease activity that causes degradation of the mRNA in the preparations. This activity was found to cosediment with all polysome size classes as well as with free mRNPs and to remain ass...

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Autors principals: Bandyopadhyay, R, Coutts, M, Krowczynska, A, Brawerman, G
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC360553/
https://ncbi.nlm.nih.gov/pubmed/2325645
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