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Cell type-specific responses of human cells to inhibition of replication licensing
Replication origins are “licensed” for a single initiation event by loading Mcm2-7 complexes during late mitosis and G1. Licensing is blocked at other cell cycle stages by the activity of cyclin-dependent kinases and a small protein called geminin. Here, we describe the effects of over-expressing a...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605503/ https://ncbi.nlm.nih.gov/pubmed/12242660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1205910 |
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