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Characterisation of ATP-Dependent Mur Ligases Involved in the Biogenesis of Cell Wall Peptidoglycan in Mycobacterium tuberculosis

ATP-dependent Mur ligases (Mur synthetases) play essential roles in the biosynthesis of cell wall peptidoglycan (PG) as they catalyze the ligation of key amino acid residues to the stem peptide at the expense of ATP hydrolysis, thus representing potential targets for antibacterial drug discovery. In...

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Détails bibliographiques
Auteurs principaux: Munshi, Tulika, Gupta, Antima, Evangelopoulos, Dimitrios, Guzman, Juan David, Gibbons, Simon, Keep, Nicholas H., Bhakta, Sanjib
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605390/
https://ncbi.nlm.nih.gov/pubmed/23555903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060143
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