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Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions

The TRAIL (TNF-related apoptosis inducing ligand) death receptors (DRs) of the tumor necrosis factor receptor superfamily (TNFRSF) can promote apoptosis and regulate antiviral immunity by maintaining immune homeostasis during infection. In turn, human cytomegalovirus (HCMV) expresses immunomodulator...

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Detalhes bibliográficos
Main Authors: Nemčovičová, Ivana, Benedict, Chris A., Zajonc, Dirk M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605307/
https://ncbi.nlm.nih.gov/pubmed/23555243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003224
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