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Structure of Human Cytomegalovirus UL141 Binding to TRAIL-R2 Reveals Novel, Non-canonical Death Receptor Interactions

The TRAIL (TNF-related apoptosis inducing ligand) death receptors (DRs) of the tumor necrosis factor receptor superfamily (TNFRSF) can promote apoptosis and regulate antiviral immunity by maintaining immune homeostasis during infection. In turn, human cytomegalovirus (HCMV) expresses immunomodulator...

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Détails bibliographiques
Auteurs principaux: Nemčovičová, Ivana, Benedict, Chris A., Zajonc, Dirk M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605307/
https://ncbi.nlm.nih.gov/pubmed/23555243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003224
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