N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

APO2L/TRAIL (TNF-related apoptosis-inducing ligand) induces death of tumor cells through two agonist receptors, TRAIL-R1 and TRAIL-R2. We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated a...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Dufour, Florent, Rattier, Thibault, Shirley, Sarah, Picarda, Gaelle, Constantinescu, Andrei Alexandru, Morlé, Aymeric, Zakaria, Al Batoul, Marcion, Guillaume, Causse, Sebastien, Szegezdi, Eva, Zajonc, Dirk Michael, Seigneuric, Renaud, Guichard, Gilles, Gharbi, Tijani, Picaud, Fabien, Herlem, Guillaume, Garrido, Carmen, Schneider, Pascal, Benedict, Chris Alan, Micheau, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344210/
https://ncbi.nlm.nih.gov/pubmed/28186505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.150
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