Plasminogen Controls Inflammation and Pathogenesis of Influenza Virus Infections via Fibrinolysis

Detrimental inflammation of the lungs is a hallmark of severe influenza virus infections. Endothelial cells are the source of cytokine amplification, although mechanisms underlying this process are unknown. Here, using combined pharmacological and gene-deletion approaches, we show that plasminogen c...

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Autores principales: Berri, Fatma, Rimmelzwaan, Guus F., Hanss, Michel, Albina, Emmanuel, Foucault-Grunenwald, Marie-Laure, Lê, Vuong B., Vogelzang-van Trierum, Stella E., Gil, Patrica, Camerer, Eric, Martinez, Dominique, Lina, Bruno, Lijnen, Roger, Carmeliet, Peter, Riteau, Béatrice
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605290/
https://ncbi.nlm.nih.gov/pubmed/23555246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003229
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