Annexin II Incorporated into Influenza Virus Particles Supports Virus Replication by Converting Plasminogen into Plasmin

For influenza viruses to become infectious, the proteolytic cleavage of hemagglutinin (HA) is essential. This usually is mediated by trypsin-like proteases in the respiratory tract. The binding of plasminogen to influenza virus A/WSN/33 leads to the cleavage of HA, a feature determining its pathogen...

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Bibliografske podrobnosti
Main Authors: LeBouder, Fanny, Morello, Eric, Rimmelzwaan, Guus F., Bosse, Françoise, Péchoux, Christine, Delmas, Bernard, Riteau, Béatrice
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446977/
https://ncbi.nlm.nih.gov/pubmed/18448517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-08
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