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Annexin II Incorporated into Influenza Virus Particles Supports Virus Replication by Converting Plasminogen into Plasmin

For influenza viruses to become infectious, the proteolytic cleavage of hemagglutinin (HA) is essential. This usually is mediated by trypsin-like proteases in the respiratory tract. The binding of plasminogen to influenza virus A/WSN/33 leads to the cleavage of HA, a feature determining its pathogen...

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Detalhes bibliográficos
Main Authors: LeBouder, Fanny, Morello, Eric, Rimmelzwaan, Guus F., Bosse, Françoise, Péchoux, Christine, Delmas, Bernard, Riteau, Béatrice
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446977/
https://ncbi.nlm.nih.gov/pubmed/18448517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00246-08
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