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Ex Vivo and In Vivo Inhibition of Human Rhinovirus Replication by a New Pseudosubstrate of Viral 2A Protease

Human rhinoviruses (HRVs) remain a significant public health problem as they are the major cause of both upper and lower respiratory tract infections. Unfortunately, to date no vaccine or antiviral against these pathogens is available. Here, using a high-throughput yeast two-hybrid screening, we ide...

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Autors principals: Falah, Nisrine, Violot, Sébastien, Décimo, Didier, Berri, Fatma, Foucault-Grunenwald, Marie-Laure, Ohlmann, Théophile, Schuffenecker, Isabelle, Morfin, Florence, Lina, Bruno, Riteau, Béatrice, Cortay, Jean-Claude
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255852/
https://ncbi.nlm.nih.gov/pubmed/22072773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05263-11
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