Ex Vivo and In Vivo Inhibition of Human Rhinovirus Replication by a New Pseudosubstrate of Viral 2A Protease

Human rhinoviruses (HRVs) remain a significant public health problem as they are the major cause of both upper and lower respiratory tract infections. Unfortunately, to date no vaccine or antiviral against these pathogens is available. Here, using a high-throughput yeast two-hybrid screening, we ide...

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Detalhes bibliográficos
Main Authors: Falah, Nisrine, Violot, Sébastien, Décimo, Didier, Berri, Fatma, Foucault-Grunenwald, Marie-Laure, Ohlmann, Théophile, Schuffenecker, Isabelle, Morfin, Florence, Lina, Bruno, Riteau, Béatrice, Cortay, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255852/
https://ncbi.nlm.nih.gov/pubmed/22072773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05263-11
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