Ex Vivo and In Vivo Inhibition of Human Rhinovirus Replication by a New Pseudosubstrate of Viral 2A Protease

Human rhinoviruses (HRVs) remain a significant public health problem as they are the major cause of both upper and lower respiratory tract infections. Unfortunately, to date no vaccine or antiviral against these pathogens is available. Here, using a high-throughput yeast two-hybrid screening, we ide...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Falah, Nisrine, Violot, Sébastien, Décimo, Didier, Berri, Fatma, Foucault-Grunenwald, Marie-Laure, Ohlmann, Théophile, Schuffenecker, Isabelle, Morfin, Florence, Lina, Bruno, Riteau, Béatrice, Cortay, Jean-Claude
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Vaccines and Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255852/
https://ncbi.nlm.nih.gov/pubmed/22072773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05263-11
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