The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels.

We have established the human nck sequence as a new oncogene. Nck encodes one SH2 and three SH3 domains, the Src homology motifs found in nonreceptor tyrosine kinases, Ras GTPase-activating protein, phosphatidylinositol 3-kinase, and phospholipase C-gamma. Overexpression of human nck in 3Y1 rat fibr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Chou, M M, Fajardo, J E, Hanafusa, H
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360523/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1280326/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.12.5834
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker