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Enterovirus 71 Protease 2A(pro) Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses

Enterovirus 71 (EV71) is the major causative pathogen of hand, foot, and mouth disease (HFMD). Its pathogenicity is not fully understood, but innate immune evasion is likely a key factor. Strategies to circumvent the initiation and effector phases of anti-viral innate immunity are well known; less w...

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Hlavní autoři: Wang, Bei, Xi, Xueyan, Lei, Xiaobo, Zhang, Xiaoyan, Cui, Sheng, Wang, Jianwei, Jin, Qi, Zhao, Zhendong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605153/
https://ncbi.nlm.nih.gov/pubmed/23555247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003231
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