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Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels
BACKGROUND: In Escherichia coli many heterologous proteins are produced in the periplasm. To direct these proteins to the periplasm, they are equipped with an N-terminal signal sequence so that they can traverse the cytoplasmic membrane via the protein-conducting Sec-translocon. For poorly understoo...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3605120/ https://ncbi.nlm.nih.gov/pubmed/23497240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-12-24 |
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