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Power and Predictive Accuracy of Polygenic Risk Scores

Polygenic scores have recently been used to summarise genetic effects among an ensemble of markers that do not individually achieve significance in a large-scale association study. Markers are selected using an initial training sample and used to construct a score in an independent replication sampl...

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Bibliografski detalji
Glavni autor: Dudbridge, Frank
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605113/
https://ncbi.nlm.nih.gov/pubmed/23555274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003348
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