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Predictive accuracy of combined genetic and environmental risk scores

The substantial heritability of most complex diseases suggests that genetic data could provide useful risk prediction. To date the performance of genetic risk scores has fallen short of the potential implied by heritability, but this can be explained by insufficient sample sizes for estimating highl...

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Detalles Bibliográficos
Publicado en:Genet Epidemiol
Main Authors: Dudbridge, Frank, Pashayan, Nora, Yang, Jian
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847122/
https://ncbi.nlm.nih.gov/pubmed/29178508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22092
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