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Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids

Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change. Theoretical work and empirical investigation in Escherichia coli have shown that negative autoregulatio...

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Bibliografische gegevens
Hoofdauteurs: Stewart, Alexander J., Seymour, Robert M., Pomiankowski, Andrew, Reuter, Max
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605092/
https://ncbi.nlm.nih.gov/pubmed/23555226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002992
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