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Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids

Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change. Theoretical work and empirical investigation in Escherichia coli have shown that negative autoregulatio...

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Hlavní autoři: Stewart, Alexander J., Seymour, Robert M., Pomiankowski, Andrew, Reuter, Max
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605092/
https://ncbi.nlm.nih.gov/pubmed/23555226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002992
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