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Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids

Regulatory networks have evolved to allow gene expression to rapidly track changes in the environment as well as to buffer perturbations and maintain cellular homeostasis in the absence of change. Theoretical work and empirical investigation in Escherichia coli have shown that negative autoregulatio...

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Detalles Bibliográficos
Main Authors: Stewart, Alexander J., Seymour, Robert M., Pomiankowski, Andrew, Reuter, Max
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605092/
https://ncbi.nlm.nih.gov/pubmed/23555226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002992
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