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Degree dependence in rates of transcription factor evolution explains the unusual structure of transcription networks

Transcription networks have an unusual structure. In both prokaryotes and eukaryotes, the number of target genes regulated by each transcription factor, its out-degree, follows a broad tailed distribution. By contrast, the number of transcription factors regulating a target gene, its in-degree, foll...

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Bibliografiske detaljer
Main Authors: Stewart, Alexander J., Seymour, Robert M., Pomiankowski, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690470/
https://ncbi.nlm.nih.gov/pubmed/19364737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2009.0210
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