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Degree dependence in rates of transcription factor evolution explains the unusual structure of transcription networks

Transcription networks have an unusual structure. In both prokaryotes and eukaryotes, the number of target genes regulated by each transcription factor, its out-degree, follows a broad tailed distribution. By contrast, the number of transcription factors regulating a target gene, its in-degree, foll...

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Autors principals: Stewart, Alexander J., Seymour, Robert M., Pomiankowski, Andrew
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690470/
https://ncbi.nlm.nih.gov/pubmed/19364737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2009.0210
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