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Comparison of the transport of QX-314 through TRPA1, TRPM8, and TRPV1 channels
BACKGROUND: It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Dove Medical Press
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604974/ https://ncbi.nlm.nih.gov/pubmed/23525210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S41614 |
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