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Pore dilation occurs in TRPA1 but not in TRPM8 channels

Abundantly expressed in pain-sensing neurons, TRPV1, TRPA1 and TRPM8 are major cellular sensors of thermal, chemical and mechanical stimuli. The function of these ion channels has been attributed to their selective permeation of small cations (e.g., Ca(2+), Na(+ )and K(+)), and the ion selectivity h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Jun, Kim, Donghee, Bianchi, Bruce R, Cavanaugh, Eric J, Faltynek, Connie R, Kym, Philip R, Reilly, Regina M
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633278/
https://ncbi.nlm.nih.gov/pubmed/19159452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-3
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