Osteoblast-specific expression of growth hormone stimulates bone growth in transgenic mice.

Growth hormone (GH) is an important regulator of postnatal growth, acting on a wide variety of target tissues. Here, we show that local production of GH in osteoblasts is able to stimulate bone growth directly without significant systemic effects. Mice were made transgenic by microinjection of an os...

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Detalles Bibliográficos
Main Authors: Baker, A R, Hollingshead, P G, Pitts-Meek, S, Hansen, S, Taylor, R, Stewart, T A
Formato: Artigo
Idioma:Inglês
Publicado: 1992
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC360492/
https://ncbi.nlm.nih.gov/pubmed/1448085
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