Osteoblast-specific expression of growth hormone stimulates bone growth in transgenic mice.

Growth hormone (GH) is an important regulator of postnatal growth, acting on a wide variety of target tissues. Here, we show that local production of GH in osteoblasts is able to stimulate bone growth directly without significant systemic effects. Mice were made transgenic by microinjection of an os...

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Библиографические подробности
Главные авторы: Baker, A R, Hollingshead, P G, Pitts-Meek, S, Hansen, S, Taylor, R, Stewart, T A
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC360492/
https://ncbi.nlm.nih.gov/pubmed/1448085
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