The kinase activity of the Helicobacter pylori Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase is sensitive to distal mutations in its putative ammonia tunnel

The Helicobacter pylori (Hp) Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase (AdT) plays important roles in indirect aminoacylation and translational fidelity. AdT has two active sites, in two separate subunits. Kinetic studies have suggested that interdomain communication occurs between these subunits...

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Detalhes bibliográficos
Main Authors: Zhao, Liangjun, Dewage, Sajeewa W., Bell, Michael J., Chang, Keng-Ming, Fatma, Shirin, Joshi, Nilesh, Silva, Gayathri, Cisneros, G. Andrés, Hendrickson, Tamara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604897/
https://ncbi.nlm.nih.gov/pubmed/22229412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201143x
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