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Computational Analysis of Ammonia Transfer Along Two Intramolecular Tunnels in Staphylococcus aureus Glutamine-Dependent Amidotransferase (GatCAB)

Most bacteria and all archaea misacylate the tRNAs corresponding to Asn and Gln with Asp and Glu (Asp-tRNA(Asn) and Glu-tRNA(Gln)). The GatCAB enzyme of most bacteria converts misacylated Glu-tRNA(Gln) to Gln-tRNA(Gln) in order to enable the incorporation of glutamine during protein synthesis. The c...

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Pubblicato in:J Phys Chem B
Autori principali: Dewage, Sajeewa Walimuni, Cisneros, G. Andrés
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5639903/
https://ncbi.nlm.nih.gov/pubmed/25654336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp5123568
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