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A new role for Ran in ensuring precise duplication of chromosomal DNA

To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.

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Bibliografske podrobnosti
Glavni avtor: Blow, J. Julian
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604807/
https://ncbi.nlm.nih.gov/pubmed/12679026
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