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A new role for Ran in ensuring precise duplication of chromosomal DNA
To prevent re-replication of DNA, the licensing of replication origins is inhibited in S phase and G2. New work shows that the small GTPase Ran can directly inhibit licensing inside nuclei once CDKs are active late in the cell cycle.
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604807/ https://ncbi.nlm.nih.gov/pubmed/12679026 |
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