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GFAP expression as an indicator of disease severity in mouse models of Alexander disease
AxD (Alexander disease) is a rare disorder caused by heterozygous mutations in GFAP (glial fibrillary acidic protein) resulting in accumulation of the GFAP protein and elevation of Gfap mRNA. To test whether GFAP itself can serve as a biomarker of disease status or progression, we investigated two i...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Neurochemistry
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604736/ https://ncbi.nlm.nih.gov/pubmed/23432455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20130003 |
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