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RNA polymerase II acts as an RNA-dependent RNA polymerase to extend and destabilize a non-coding RNA

RNA polymerase II (Pol II) is a well-characterized DNA-dependent RNA polymerase, which has also been reported to have RNA-dependent RNA polymerase (RdRP) activity. Natural cellular RNA substrates of mammalian Pol II, however, have not been identified and the cellular function of the Pol II RdRP acti...

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Autori principali: Wagner, Stacey D, Yakovchuk, Petro, Gilman, Benjamin, Ponicsan, Steven L, Drullinger, Linda F, Kugel, Jennifer F, Goodrich, James A
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Molecular Biology Organization 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604716/
https://ncbi.nlm.nih.gov/pubmed/23395899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.18
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