Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin.

Sodium butyrate reversibly inhibits muscle differentiation and blocks the expression of many muscle-specific genes in both proliferating myoblasts and differentiated myotubes. We investigated the role of the basic helix-loop-helix (bHLH) myogenic determinator proteins MyoD and myogenin in this inhib...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Johnston, L A, Tapscott, S J, Eisen, H
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 1992
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5123-5130.1992
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