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Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin.

Sodium butyrate reversibly inhibits muscle differentiation and blocks the expression of many muscle-specific genes in both proliferating myoblasts and differentiated myotubes. We investigated the role of the basic helix-loop-helix (bHLH) myogenic determinator proteins MyoD and myogenin in this inhib...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Johnston, L A, Tapscott, S J, Eisen, H
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5123
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