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Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin.
Sodium butyrate reversibly inhibits muscle differentiation and blocks the expression of many muscle-specific genes in both proliferating myoblasts and differentiated myotubes. We investigated the role of the basic helix-loop-helix (bHLH) myogenic determinator proteins MyoD and myogenin in this inhib...
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| Publié dans: | Mol Cell Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5123 |
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