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A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.

SH2 (src homology region 2) domains are implicated in protein-protein interactions involved in signal transduction pathways. Isolated SH2 domains bind proteins that are tyrosine phosphorylated. A novel, phosphotyrosine-independent binding interaction between BCR, the Philadelphia chromosome breakpoi...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Muller, A J, Pendergast, A M, Havlik, M H, Puil, L, Pawson, T, Witte, O N
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC360442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1383690/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.11.5087
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