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Leveraging fluorinated glucosamine action to boost anti-tumor immunity
N-acetyllactosaminyl glycans are key regulators of the vitality and effector function of anti-tumor T cells. When galectin-1 (Gal-1) binds N-acetyllactosamines on select membrane glycoproteins on anti-tumor T cells, these cells either undergo apoptosis or become immunoregulatory. Methods designed to...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604137/ https://ncbi.nlm.nih.gov/pubmed/23219268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.11.003 |
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