DEPLETION OF DENDRITIC CELLS DELAYS OVARIAN CANCER PROGRESSION BY BOOSTING ANTI-TUMOR IMMUNITY

Dendritic cells (DCs) and cytokines that expand myeloid progenitors are widely used to treat cancer. Here we demonstrate that CD11c(+)DEC205(+) DCs co-expressing α-Smooth Muscle Actin and VE-Cadherin home to perivascular areas in the ovarian cancer microenvironment and are required for the maintenan...

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Auteurs principaux: Huarte, Eduardo, Cubillos-Ruiz, Juan R., Nesbeth, Yolanda C., Scarlett, Uciane K., Martinez, Diana G., Buckanovich, Ronald J., Benencia, Fabian, Stan, Radu V., Keler, Tibor, Sarobe, Pablo, Sentman, Charles L., Conejo-Garcia, Jose R.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742361/
https://ncbi.nlm.nih.gov/pubmed/18768667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1167
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