Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae

Chronological aging of budding yeast cells results in a reduction in subsequent replicative life span through unknown mechanisms. Here we show that dietary restriction during chronological aging delays the reduction in subsequent replicative life span up to at least 23 days of chronological age. We...

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Main Authors: Delaney, Joe R., Murakami, Christopher, Chou, Annie, Carr, Daniel, Schleit, Jennifer, Sutphin, George L., An, Elroy H., Castanza, Anthony S., Fletcher, Marissa, Goswami, Sarani, Higgins, Sean, Holmberg, Mollie, Hui, Jessica, Jelic, Monika, Jeong, Ki-Soo, Kim, Jin R., Klum, Shannon, Liao, Eric, Lin, Michael S., Lo, Winston, Miller, Hillary, Moller, Richard, Peng, Zhao J., Pollard, Tom, Pradeep, Prarthana, Pruett, Dillon, Rai, Dilreet, Ros, Vanessa, Schuster, Alex, Singh, Minnie, Spector, Benjamin L., Wende, Helen Vander, Wang, Adrienne M., Wasko, Brian M., Olsen, Brady, Kaeberlein, Matt
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604125/
https://ncbi.nlm.nih.gov/pubmed/23235143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.12.001
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